Senior Research Associate, Peptide Chemistry
Flagship Pioneering
Company Overview: Abiologics, Inc. is a privately held, early-stage biotechnology company on a mission to make biology better through an innovative therapeutic modality. We are pioneering the development of Synteins™, a transformational class of macromolecular medicines unlocked by novel synthetic and computational technologies. Abiologics is actively seeking exceptional scientists who are passionate about driving therapeutic modality innovation in biotechnology.
Abiologics was founded in Flagship Pioneering’s venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Generate Biomedicines were conceived and created. Since Flagship’s founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures resulting in more than 500 issued patents and more than 50 clinical trials for novel therapeutic agents.
Position Summary:
This position offers a terrific opportunity to discover a new class of groundbreaking medicines. The successful candidate will work closely with a group of skilled scientists to design, synthesize, and analyze complex peptides for therapeutic applications. This role requires a deep understanding of peptide chemistry and problem-solving skills to develop novel chemistries and creating a new class of macromolecular medicines called Synteins™.
Key Responsibilities:
- Apply a combination of solid-phase peptide synthesis, conjugation chemistries, and automation technologies to synthesize new macromolecules
- Purify and analyze macromolecules using modern instrumentation
- Independently troubleshoot challenging technical, experimental, and instrumental issues
- Evaluate macromolecular properties using various biophysical and functional assays
- Meticulously record and analyze data with a minimum of oversight
- Prepare and maintain laboratory reagents and instruments
- Regularly summarize progress of work in oral and written format.
- Stay informed of the latest developments in peptide chemistry and related fields through continuous learning
Qualifications:
- BS or MS degree or equivalent experience in chemistry, chemical engineering, or biochemistry and 2+ years of industry experience.
- Experience in either or all the following is a plus:
- organic synthesis including solid-phase peptide synthesis
- reaction design, optimization, and automation
- analytical techniques LCMS, HPLC, FPLC, UV-VIS, NMR, FT-IR, CD
- Enthusiasm, independence, and a willingness to learn in a fast-paced, entrepreneurial and result-oriented environment.
- Excellent written and verbal communication skills.
- Committed to working collaboratively with an interdisciplinary team.
More About Flagship Pioneering
Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.
Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
