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FL114: Senior Research Associate, Discovery Biology

Flagship Pioneering

Flagship Pioneering

Cambridge, MA, USA
Posted on Aug 6, 2025

About the Role:

FL114, Inc. is seeking an outstanding Senior Research Associate to join our Discovery Biology team. We’re looking for a versatile in vitro biologist to assist in the development and advancement of our epigenetic editing programs, from early discovery research to preclinical development and beyond. The successful candidate will be an enthusiastic, detail-oriented, adaptive, and highly motivated individual with a passion for bringing novel medicines to patients. Applicants should be comfortable working on a fast-paced, cross-functional scientific team.

Key Responsibilities:

  • Independently design, execute, and analyze in vitro biology experiments for target validation and evaluation of epigenetic controllers
  • Perform routine and specialized cell culture procedures, including the maintenance and handling of primary human/mouse cells and established cell lines
  • Conduct downstream analytical techniques on cell and tissue samples including qPCR, western blot and ELISA.
  • Maintain accurate and detailed laboratory records of experimental design, protocols, raw data, and analyzed results.
  • Assist in management of day-to-day laboratory operations including maintenance of equipment, as well as reagent tracking, ordering, and receiving

Required Skills:

  • Well-versed in mammalian cell culture with extensive experience using primary cell cultures across different therapeutic areas. Experience with stem cell differentiation protocols a plus
  • Proficiency in biochemical and molecular techniques including (but not limited to) DNA/RNA/protein isolation, qPCR, gene silencing techniques (siRNA/CRISPR/TALEN), immunoassays (ELISA/Luminex), flow cytometry and western blot
  • Adaptive and detail-oriented with excellent time management and organizations skills
  • Exceptional communication and collaboration skills, with a proven ability to work effectively across interdisciplinary teams.

Required Qualifications:

  • BS or MS in Cell or Molecular Biology, Biochemistry, or related field with 3+ years of experience. Industry experience preferred.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

About Flagship Pioneering:

Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture. What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
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